Injectables, cosmetics-fragrance, next-gen materials

Many drugs dissolve poorly in water, making them hard to formulate and often forcing chemical modification such as prodrugs or salt formation. BigBasin works toward turning poorly soluble drugs into stable aqueous dispersions through colloidalization and dispersion, without altering the molecule. We choose carriers, including biodegradable polymers such as polylactic acid (PLA), to fit the goal; the carrier keeps the active stable in storage, releases it at the designed rate after administration, and then degrades on its own. We meet particle-size, stability, and safety requirements step by step, with injectable formulations as the ultimate target.

Actives such as retinol and vitamin C derivatives readily oxidize and lose potency inside a formulation, while volatile aroma molecules spend themselves in one burst. Both problems are the same at heart: keep an unstable molecule safe inside a carrier, then release it at the intended time and rate. BigBasin's dispersion and encapsulation technology forms actives into a stable colloid, shields them from the environment, and releases them at a controlled rate; the same principle tempers a fragrance's initial burst and shapes its release curve from top note to base note.

Underneath the dispersion platform sits a broader competence in polymers: synthesis and modification of carrier polymers, design of functional composites that join dissimilar materials, and characterization at the colloid, interface, and particle level. On this base we take on new materials problems without being confined to a fixed application. Uses not yet defined, in energy, environmental, or bio materials, start from a partner's need and are defined together.